BDBM50095313 CHEMBL3589892

SMILES CNC(=O)c1cnc(N)c(c1)-c1cc(Cl)cc(Cl)c1Cl

InChI Key InChIKey=DIFLLTOFIQIMEY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095313   

TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095313(CHEMBL3589892)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human Nav1.3 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095313(CHEMBL3589892)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human Nav1.2 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095313(CHEMBL3589892)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095313(CHEMBL3589892)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human Nav1.7 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed