BDBM50095320 2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenol::CHEMBL150438

SMILES COc1ccc(OCc2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key InChIKey=PJCOYSVLNFEHHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095320   

TargetTubulin beta-1 chain(Homo sapiens (Human))
University Of Salford

Curated by ChEMBL
LigandPNGBDBM50095320(2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenol | ...)
Affinity DataIC50:  2.10E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A/beta chain(Sus scrofa (Pig))
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50095320(2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenol | ...)
Affinity DataIC50:  2.26E+5nMAssay Description:Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A/beta chain(Sus scrofa (Pig))
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50095320(2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenol | ...)
Affinity DataIC50:  2.25E+4nMAssay Description:Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed