BDBM50095399 5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid methyl ester::CHEMBL279377::methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2-carboxylate

SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C

InChI Key InChIKey=HXUFSIDDYWPGJO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095399   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  413nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  248nMAssay Description:Inhibition of p38 alpha2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed