BDBM50095411 5-tert-Butyl-3-[3-(4-hydroxy-phenyl)-ureido]-thiophene-2-carboxylic acid methyl ester::CHEMBL279560::methyl 5-tert-butyl-3-(3-(4-hydroxyphenyl)ureido)thiophene-2-carboxylate

SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccc(O)cc1)C(C)(C)C

InChI Key InChIKey=BAXKULRSDFFZQS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095411   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095411(5-tert-Butyl-3-[3-(4-hydroxy-phenyl)-ureido]-thiop...)
Affinity DataIC50:  610nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095411(5-tert-Butyl-3-[3-(4-hydroxy-phenyl)-ureido]-thiop...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095411(5-tert-Butyl-3-[3-(4-hydroxy-phenyl)-ureido]-thiop...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095411(5-tert-Butyl-3-[3-(4-hydroxy-phenyl)-ureido]-thiop...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed