BDBM50095598 CHEMBL70223::[4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(1-pyrimidin-4-yl-piperidin-4-yl)-methanone

SMILES Brc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCN(CC1)c1ccncn1

InChI Key InChIKey=VSGXABIFGUPLNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095598   

TargetLanosterol synthase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095598(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)
Affinity DataIC50:  116nMAssay Description:Compound was tested for its inhibition against rat OSC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095598(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)
Affinity DataIC50:  116nMAssay Description:Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095598(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)
Affinity DataIC50:  37nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed