BDBM50096228 CHEMBL3594175

SMILES CN(Cc1ccc2[nH]cnc2c1Cl)c1nccc(Nc2cc([nH]n2)[C@H]2CCN(C)C2=O)n1

InChI Key InChIKey=NWSVQMVAPKFALM-REMVQUNOSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50096228   

TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096228(CHEMBL3594175)
Affinity DataKi:  18nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096228(CHEMBL3594175)
Affinity DataKi:  950nMAssay Description:Inhibition of PAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096228(CHEMBL3594175)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096228(CHEMBL3594175)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as inhibition of MEK phosphorylation at S298More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed