BDBM50096299 CHEMBL3585451

SMILES Cc1ccc(cn1)-c1cnc(NC2CCNCC2)c2[nH]c(=O)c(C)cc12

InChI Key InChIKey=GKGLOWUWFMKJIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096299   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50096299(CHEMBL3585451)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50096299(CHEMBL3585451)
Affinity DataIC50:  3.98E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed