BDBM50096769 CHEMBL124863::Cyanoguanidine derivative

SMILES O[C@@H](CNCCc1ccc(NC(Nc2cccc(Oc3ccccc3)c2)=NC#N)cc1)c1cccnc1

InChI Key InChIKey=XKSJIETUBPNSHE-NDEPHWFRSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096769   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096769(CHEMBL124863 | Cyanoguanidine derivative)
Affinity DataIC50:  40nMAssay Description:Binding affinity to the human beta-2 adrenergic receptor assayed using [125I]-iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096769(CHEMBL124863 | Cyanoguanidine derivative)
Affinity DataEC50:  26nMAssay Description:In vitro efficacy at human beta-3 adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096769(CHEMBL124863 | Cyanoguanidine derivative)
Affinity DataIC50:  240nMAssay Description:Binding affinity for human Beta-1 adrenergic receptor using [125I]-iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed