BDBM50096906 CHEMBL154745::US10227373, Compound D-3-Deazaisoneplanocin
SMILES Nc1nccc2n(cnc12)[C@@H]1C=C(CO)[C@@H](O)[C@H]1O
InChI Key InChIKey=OMKHWTRUYNAGFG-IEBDPFPHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50096906
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of SAH hydrolase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human placental AdoHcy hydrolase expressed in Escherichia coli BL21 using AdoHcy as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 3.19nMAssay Description:As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...More data for this Ligand-Target Pair