BDBM50097396 CHEMBL3586444

SMILES Cc1ccncc1-c1cccc2c(N)c(nnc12)C(N)=O

InChI Key InChIKey=YHEHDRMGAHEUOQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097396   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataEC50:  2.86E+4nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed