BDBM50097970 3-[4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester::CHEMBL422565

SMILES CC(C)(C)OC(=O)N1CCC(C1)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12

InChI Key InChIKey=ZXAJVNQEBDPRSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097970   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097970(3-[4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  8nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097970(3-[4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibition of c-Src mediated phosphorylation of Fak in IC8.1 fibroblast cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed