BDBM500981 (S)-7-((5-(2- (methoxymeth- yl)morpho- lino)pyridin-2- yl)amino)-4- (7-methyl-7H- pyrrolo[2,3- d|pyrimidin-4- yl)isoindolin- 1-one::US11021481, Compound I-650::US11078201, Compound I-650::US11548890, Compound I-650
SMILES COC[C@H]1CN(CCO1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2ncnc3n(C)ccc23)nc1
InChI Key InChIKey=XOXNSJDLHGDPRJ-QGZVFWFLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 500981
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair