BDBM50098753 6-{4-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-2-chloro-phenylsulfanyl}-2,3-dihydro-benzo[1,4]dioxine-2-carboxylic acid dimethylamide::CHEMBL19675

SMILES CN(C)C(=O)C1COc2cc(Sc3ccc(\C=C\C(=O)N4CCN(CC4)C(C)=O)cc3Cl)ccc2O1

InChI Key InChIKey=YZCNYQLRQDZAIE-WEVVVXLNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098753   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098753(6-{4-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-...)
Affinity DataIC50:  510nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed