BDBM50098755 1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(3-dimethylaminomethyl-1-ethyl-1H-indol-7-ylsulfanyl)-phenyl]-propenone::CHEMBL277769

SMILES CCn1cc(CN(C)C)c2cccc(Sc3ccc(\C=C\C(=O)N4CCN(CC4)C(C)=O)cc3Cl)c12

InChI Key InChIKey=DOTRUZSRWNXWJD-ZRDIBKRKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098755   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098755(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(3-dimet...)
Affinity DataIC50:  100nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (100-110)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed