BDBM50098767 5-{4-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-2-chloro-phenylsulfanyl}-6-chloro-1,3-dihydro-benzoimidazol-2-one::CHEMBL281334

SMILES CC(=O)N1CCN(CC1)C(=O)C=Cc1ccc(Sc2cc3[nH]c(=O)[nH]c3cc2Cl)c(Cl)c1

InChI Key InChIKey=MGQXQCUUTIULTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098767   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098767(5-{4-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-...)
Affinity DataIC50:  790nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (728-860)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed