BDBM50098769 1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(5-ethoxy-2,3-dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-phenyl]-propenone::CHEMBL19856

SMILES CCOc1c(Sc2ccc(\C=C\C(=O)N3CCN(CC3)C(C)=O)cc2Cl)ccc2OCCOc12

InChI Key InChIKey=YSCQEWQIIQUHAR-WEVVVXLNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098769   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098769(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(5-ethox...)
Affinity DataIC50:  100nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (90-100)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed