BDBM50099307 (4-Fluoro-phenyl)-[(3S,4R)-4-(4-fluoro-phenyl)-1-methyl-pyrrolidin-3-yl]-methanone::CHEMBL13425

SMILES CN1C[C@H]([C@@H](C1)c1ccc(F)cc1)C(=O)c1ccc(F)cc1

InChI Key InChIKey=BRTUVYIEVZPBTD-DLBZAZTESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099307   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099307((4-Fluoro-phenyl)-[(3S,4R)-4-(4-fluoro-phenyl)-1-m...)
Affinity DataKi:  380nMAssay Description:Inhibition of [3H]5-HT uptake at Serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099307((4-Fluoro-phenyl)-[(3S,4R)-4-(4-fluoro-phenyl)-1-m...)
Affinity DataKi:  800nMAssay Description:Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099307((4-Fluoro-phenyl)-[(3S,4R)-4-(4-fluoro-phenyl)-1-m...)
Affinity DataKi:  3.96E+3nMAssay Description:Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed