BDBM50099310 ((3S,4R)-1,4-Diphenyl-pyrrolidin-3-yl)-thiophen-2-yl-methanone::CHEMBL428112

SMILES O=C([C@@H]1CN(C[C@H]1c1ccccc1)c1ccccc1)c1cccs1

InChI Key InChIKey=NYKDONRYYINACD-RBUKOAKNSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099310   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099310(((3S,4R)-1,4-Diphenyl-pyrrolidin-3-yl)-thiophen-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099310(((3S,4R)-1,4-Diphenyl-pyrrolidin-3-yl)-thiophen-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]5-HT uptake at Serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099310(((3S,4R)-1,4-Diphenyl-pyrrolidin-3-yl)-thiophen-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed