BDBM50099339 2-(3,5-Difluoro-phenoxy)-4-[5-(4-fluoro-phenyl)-3-piperidin-4-yl-3H-imidazol-4-yl]-pyrimidine::CHEMBL14339

SMILES Fc1ccc(cc1)-c1ncn(C2CCNCC2)c1-c1ccnc(Oc2cc(F)cc(F)c2)n1

InChI Key InChIKey=IXQGHOZDNBWZOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099339   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099339(2-(3,5-Difluoro-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50:  209nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50099339(2-(3,5-Difluoro-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human BRDT bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50099339(2-(3,5-Difluoro-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human BRDT bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50099339(2-(3,5-Difluoro-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed