BDBM50099347 2-(3,4-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-piperidin-4-yl-3H-imidazol-4-yl]-pyrimidine::CHEMBL13880

SMILES Cc1ccc(Oc2nccc(n2)-c2c(ncn2C2CCNCC2)-c2ccc(F)cc2)cc1C

InChI Key InChIKey=ZPVIXTLWEIXXCD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099347   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099347(2-(3,4-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099347(2-(3,4-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50099347(2-(3,4-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human BRDT bromodomain 2 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50099347(2-(3,4-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50099347(2-(3,4-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human BRDT bromodomain 1 (unknown origin) expressed in Escherichia coli Bl21(DE3) by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed