BDBM50099353 2-(2,6-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-piperidin-4-yl-3H-imidazol-4-yl]-pyrimidine::CHEMBL277521

SMILES Cc1cccc(C)c1Oc1nccc(n1)-c1c(ncn1C1CCNCC1)-c1ccc(F)cc1

InChI Key InChIKey=WYNFNSAQVGSQMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099353   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50099353(2-(2,6-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50:  34.3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50099353(2-(2,6-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)
Affinity DataIC50:  34nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed