BDBM50099829 CHEMBL3319584

SMILES COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)C2=C(C)c3ccccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=PNVONHQAGBQVCW-LURJTMIESA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50099829   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  3nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  76nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  764nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  764nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  76nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099829(CHEMBL3319584)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed