BDBM50099967 (1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine::CHEMBL287591::D3RKN_95

SMILES C(c1ccccc1)n1ccc2cc(Nc3ncnc4ccccc34)ccc12

InChI Key InChIKey=HSEFNFDMTWKPLM-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099967   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Research Biomet. Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50099967((1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine | C...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of c-erbB-2 overexpressing HB4a cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50099967((1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine | C...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50099967((1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine | C...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Rattus norvegicus)
Research Biomet. Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50099967((1-Benzyl-1H-indol-5-yl)-quinazolin-4-yl-amine | C...)
Affinity DataIC50:  90nMAssay Description:Inhibition of rat Receptor protein-tyrosine kinase erbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed