BDBM50100000 1-(4-Chloro-phenyl)-4-[3-(3-phenoxy-benzyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one::CHEMBL30646

SMILES Clc1ccc(cc1)N1CCN(Cc2cncn2Cc2cccc(Oc3ccccc3)c2)CC1=O

InChI Key InChIKey=BPPQKJVLUWXNRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100000   

LigandPNGBDBM50100000(1-(4-Chloro-phenyl)-4-[3-(3-phenoxy-benzyl)-3H-imi...)
Affinity DataIC50:  136nMAssay Description:In vitro inhibition against human Geranylgeranyl transferase type I catalyzed by incorporation of [3H]- GGPP (geranylgeranyl pyrophosphate) into biot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50100000(1-(4-Chloro-phenyl)-4-[3-(3-phenoxy-benzyl)-3H-imi...)
Affinity DataIC50:  670nMAssay Description:In vitro inhibition against human Farnesyltransferase catalyzed by incorporation of [3H]- FPP into recombinant Ras-CVIMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed