BDBM50100087 5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfonylmethyl]-pentanoic acid hydroxyamide; hydrochloride::CHEMBL542088

SMILES ONC(=O)C(CCCc1ccccc1)CS(=O)(=O)c1ccc(cc1)C(=O)c1ccncc1

InChI Key InChIKey=FFXPIMSNULYFOV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100087   

TargetInterstitial collagenase(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed