BDBM50100097 2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamide::CHEMBL299946

SMILES ONC(=O)CN1Cc2c(Cl)cccc2NS1(=O)=O

InChI Key InChIKey=MNAUWMOCDLCGGF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50100097   

TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Collagenase-3, matrix metalloptroteinase-13 (MMP-13).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition against endothelin-converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50:  120nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human macrophage elastase, matrix metalloproteinase-12 (MMP-12).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed