BDBM50100285 4-{5-[4-(3-Chloro-phenyl)-2-(2-methanesulfonyl-ethyl)-5-oxo-piperazin-1-ylmethyl]-4-methyl-imidazol-1-ylmethyl}-benzonitrile::CHEMBL22356
SMILES Cc1ncn(Cc2ccc(cc2)C#N)c1CN1CC(=O)N(CC1CCS(C)(=O)=O)c1cccc(Cl)c1
InChI Key InChIKey=QUJNUEZQIXVXCJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50100285
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 475nMAssay Description:Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair