BDBM50100290 3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-N-phenyl-benzamide::CHEMBL25439

SMILES O=C(Nc1ccccc1)c1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1

InChI Key InChIKey=GBDDVKMRTGPCDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100290   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50100290(3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-N-phenyl...)
Affinity DataIC50:  38nMAssay Description:Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50100290(3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-N-phenyl...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed