BDBM50100302 2-(3-Chloro-phenoxy)-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL22847

SMILES Clc1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1

InChI Key InChIKey=UJBRGSBCWPZFDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100302   

LigandPNGBDBM50100302(2-(3-Chloro-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50:  53nMAssay Description:Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50100302(2-(3-Chloro-phenoxy)-4-imidazol-1-ylmethyl-benzoni...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed