BDBM501009 7-((6- ((3aS, 6aS)- hexahydropyrr olo[3,4- b]pyrrol- 1(2H)-yl)-4- methoxypyridin- 2-yl)amino)- 4-(1-methyl- 1H-pyrrolo[2,3- b]pyridin-4- yl)-2,3- dihydro-1H- pyrrolo[3,4- c]pyridin-1-one::US11021481, Compound I-681::US11078201, Compound I-681::US11548890, Compound I-681
SMILES COc1cc(Nc2cnc(c3CNC(=O)c23)-c2ccnc3n(C)ccc23)nc(c1)N1CC[C@H]2CNC[C@@H]12
InChI Key InChIKey=SWYXSKJJQYPMEJ-YCRPNKLZSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 501009
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair