BDBM50100902 CHEMBL288067::N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-yl)-ethyl]-N-hydroxy-formamide

SMILES CN1C(=O)N(CC(COc2ccc(cc2)-c2ccc(cc2)C#N)N(O)C=O)C(=O)C1(C)C

InChI Key InChIKey=MIXVCULNWAELJE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100902   

TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(CHEMBL288067 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  9.10E+3nMAssay Description:In vitro inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(CHEMBL288067 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  2.30E+6nMAssay Description:In vitro inhibition of Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(CHEMBL288067 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  58nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(CHEMBL288067 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(CHEMBL288067 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  5.80E+4nMAssay Description:In vitro inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed