BDBM50100906 CHEMBL39035::N-[2-(4'-Cyano-biphenyl-4-yloxy)-1-(4-fluoro-phenyl)-ethyl]-N-hydroxy-formamide

SMILES ON(C=O)C(COc1ccc(cc1)-c1ccc(cc1)C#N)c1ccc(F)cc1

InChI Key InChIKey=BXGFONUNBZSLOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100906   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100906(CHEMBL39035 | N-[2-(4'-Cyano-biphenyl-4-yloxy)-1-(...)
Affinity DataIC50:  4.80E+5nMAssay Description:In vitro inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100906(CHEMBL39035 | N-[2-(4'-Cyano-biphenyl-4-yloxy)-1-(...)
Affinity DataIC50:  3.00E+5nMAssay Description:In vitro inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100906(CHEMBL39035 | N-[2-(4'-Cyano-biphenyl-4-yloxy)-1-(...)
Affinity DataIC50: >1.00E+7nMAssay Description:In vitro inhibition of Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed