BDBM50100915 CHEMBL434204::N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(2,5-dioxo-pyrrolidin-1-yl)-ethyl]-N-hydroxy-formamide

SMILES ON(C=O)C(COc1ccc(cc1)-c1ccc(cc1)C#N)CN1C(=O)CCC1=O

InChI Key InChIKey=ZVOOITOWQYKKKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100915   

TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100915(CHEMBL434204 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  1.10E+4nMAssay Description:In vitro inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100915(CHEMBL434204 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50: >1.00E+7nMAssay Description:In vitro inhibition of Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100915(CHEMBL434204 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  5.20E+3nMAssay Description:In vitro inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed