BDBM50101160 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL297428

SMILES CC1C2Cc3ccc(cc3C1(C)CCN2CC1CC1)C(N)=O

InChI Key InChIKey=FAVQVALXVLMHLE-UHFFFAOYSA-N

Data  11 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101160   

TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataEC50:  8.80nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataEC50:  2.40nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataEC50:  1nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed