BDBM50101232 CHEMBL50552::{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-pyrrolidin-1-yl-methanone

SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1cccnc1)C(=O)N1CCCC1

InChI Key InChIKey=YKYNGDCUULJEHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50101232   

TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101232(CHEMBL50552 | {2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyr...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of [125I]-buserelin binding to human Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101232(CHEMBL50552 | {2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyr...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed