BDBM50101620 CHEMBL80823::N-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl}-acetamide

SMILES CC(=O)NC[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C

InChI Key InChIKey=CVBFXYSQQQVPOA-UGKGYDQZSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101620   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101620(CHEMBL80823 | N-{2-[2-Amino-3-(4-hydroxy-2,6-dimet...)
Affinity DataEC50:  1.5nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101620(CHEMBL80823 | N-{2-[2-Amino-3-(4-hydroxy-2,6-dimet...)
Affinity DataIC50:  16nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101620(CHEMBL80823 | N-{2-[2-Amino-3-(4-hydroxy-2,6-dimet...)
Affinity DataIC50:  9.38E+3nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101620(CHEMBL80823 | N-{2-[2-Amino-3-(4-hydroxy-2,6-dimet...)
Affinity DataIC50:  0.790nMAssay Description:Binding affinity at cloned human delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed