BDBM50101630 CHEMBL307889::N-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl}-2,2-dimethyl-propionamide

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1CNC(=O)C(C)(C)C

InChI Key InChIKey=OWRPMMAPXSPOTG-REWPJTCUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101630   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101630(CHEMBL307889 | N-{2-[2-Amino-3-(4-hydroxy-2,6-dime...)
Affinity DataIC50:  0.790nMAssay Description:Binding affinity at cloned human delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101630(CHEMBL307889 | N-{2-[2-Amino-3-(4-hydroxy-2,6-dime...)
Affinity DataIC50:  25nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101630(CHEMBL307889 | N-{2-[2-Amino-3-(4-hydroxy-2,6-dime...)
Affinity DataIC50:  394nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed