BDBM50102343 1-(2,5-Dimethyl-thiophen-3-yl)-3-(4-naphthalen-1-yl-piperazin-1-yl)-propan-1-one::1-(2,5-dimethylthiophen-3-yl)-3-(4-(naphthalen-1-yl)piperazin-1-yl)propan-1-one::CHEMBL441481

SMILES Cc1cc(C(=O)CCN2CCN(CC2)c2cccc3ccccc23)c(C)s1

InChI Key InChIKey=DLIRLZHKNRWFNJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102343   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102343(1-(2,5-Dimethyl-thiophen-3-yl)-3-(4-naphthalen-1-y...)
Affinity DataKi:  100nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102343(1-(2,5-Dimethyl-thiophen-3-yl)-3-(4-naphthalen-1-y...)
Affinity DataKi:  100nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102343(1-(2,5-Dimethyl-thiophen-3-yl)-3-(4-naphthalen-1-y...)
Affinity DataKi:  370nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102343(1-(2,5-Dimethyl-thiophen-3-yl)-3-(4-naphthalen-1-y...)
Affinity DataKi:  5.01E+3nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed