BDBM50102414 5-(2,5-Dihydroxy-benzylamino)-N-hexyl-2-hydroxy-benzamide::CHEMBL122397

SMILES CCCCCCNC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O

InChI Key InChIKey=MFNPKZBKWKGSLK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50102414   

TargetEpidermal growth factor receptor(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102414(5-(2,5-Dihydroxy-benzylamino)-N-hexyl-2-hydroxy-be...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-2B chain(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102414(5-(2,5-Dihydroxy-benzylamino)-N-hexyl-2-hydroxy-be...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50102414(5-(2,5-Dihydroxy-benzylamino)-N-hexyl-2-hydroxy-be...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human COX-2 by enzyme immune assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50102414(5-(2,5-Dihydroxy-benzylamino)-N-hexyl-2-hydroxy-be...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of 5-LOX (unknown origin) by enzyme immune assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102414(5-(2,5-Dihydroxy-benzylamino)-N-hexyl-2-hydroxy-be...)
Affinity DataIC50: 900nMAssay Description:Displacement of [gamma-32P]-ATP from Epidermal growth factor receptor in A431 cell-free extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article