BDBM50102578 7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL86654

SMILES COC(=O)C1C2[C@H](O)CC(CC1c1ccc3ccccc3c1)N2C

InChI Key InChIKey=OKISLTVQJOBHIW-DBMMPTTLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102578   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102578(7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  94nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102578(7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102578(7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  94nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102578(7-Hydroxy-8-methyl-3-naphthalen-2-yl-8-aza-bicyclo...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed