BDBM50102789 2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-carboxamidine::2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-6-BROMO-4-METHYLBENZENOLATE::CHEMBL95097

SMILES Cc1cc(Br)c(O)c(c1)-c1nc2ccc(cc2[nH]1)C(N)=N

InChI Key InChIKey=XKCHOMIJYLHXLI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102789   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102789(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-benzoimid...)
Affinity DataKi:  280nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102789(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-benzoimid...)
Affinity DataKi:  570nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102789(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-benzoimid...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102789(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-benzoimid...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102789(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-benzoimid...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102789(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-benzoimid...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed