BDBM50102792 2-(2-Hydroxy-3-bromo-5-nitro-phenyl)-1H-indole-5-carboxamidine::CHEMBL316334

SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(cc(Br)c1O)[N+]([O-])=O

InChI Key InChIKey=YCMUIWWODVYRLS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102792   

TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102792(2-(2-Hydroxy-3-bromo-5-nitro-phenyl)-1H-indole-5-c...)
Affinity DataKi:  78nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102792(2-(2-Hydroxy-3-bromo-5-nitro-phenyl)-1H-indole-5-c...)
Affinity DataKi:  240nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102792(2-(2-Hydroxy-3-bromo-5-nitro-phenyl)-1H-indole-5-c...)
Affinity DataKi:  280nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102792(2-(2-Hydroxy-3-bromo-5-nitro-phenyl)-1H-indole-5-c...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102792(2-(2-Hydroxy-3-bromo-5-nitro-phenyl)-1H-indole-5-c...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102792(2-(2-Hydroxy-3-bromo-5-nitro-phenyl)-1H-indole-5-c...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed