BDBM50103573 CHEMBL3337583

SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(OC(F)(F)F)ccc1-n1cccc21

InChI Key InChIKey=NISDATURCATRJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103573   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50103573(CHEMBL3337583)
Affinity DataIC50:  181nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50103573(CHEMBL3337583)
Affinity DataIC50:  19nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed