BDBM50103575 CHEMBL3337585

SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(ccc1-n1cccc21)C(F)(F)F

InChI Key InChIKey=RGKGDWOKTINAMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103575   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50103575(CHEMBL3337585)
Affinity DataIC50:  217nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50103575(CHEMBL3337585)
Affinity DataIC50:  9nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed