BDBM50103637 CHEMBL1439622::CS115

SMILES COc1ccc2c(C)nc(Nc3nc(C)cc(O)n3)nc2c1

InChI Key InChIKey=JGBVKLZKXUSJRA-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103637   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50103637(CHEMBL1439622 | CS115)
Affinity DataKd: >1.00E+5nMAssay Description:OctetRed_Method1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50103637(CHEMBL1439622 | CS115)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT1 phosphorylation in human Cal33 cells by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50103637(CHEMBL1439622 | CS115)
Affinity DataIC50:  3.39E+4nMAssay Description:Inhibition of IL-6-induced STAT3 phosphorylation in human Cal33 cells assessed as nuclear translocation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50103637(CHEMBL1439622 | CS115)
Affinity DataKd: >1.00E+5nMAssay Description:OctetRed_Method1More data for this Ligand-Target Pair
In DepthDetails PubMed