BDBM50103649 CHEMBL3337620

SMILES Cc1ccc2c(C)nc(Nc3nc(=O)cc(C)[nH]3)nc2c1

InChI Key InChIKey=PMJSZWUAOZHRJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103649   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50103649(CHEMBL3337620)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of IL-6-induced STAT3 phosphorylation in human Cal33 cells assessed as nuclear translocation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50103649(CHEMBL3337620)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of IFNgamma-induced STAT1 phosphorylation in human Cal33 cells by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed