BDBM50104285 CHEMBL3593716

SMILES CN1CCN(CC1)c1nc2CCCCc2c(=O)[nH]1

InChI Key InChIKey=SQCWABLHLAOJBR-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50104285   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  300nMAssay Description:Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human ARTD7 (460 to 656) using 250 nM NAD substrate after 2 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ARTD10 (809 to 1017) using 500 nM NAD substrate after 2.5 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human TNKS1 (1030 to 1317) using NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of full-length human ARTD3 using 500 nM NAD substrate after 1 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of full-length human ARTD2 using 500 nM NAD substrate after 3 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of full-length human ARTD1 using 500 nM NAD substrate after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104285(CHEMBL3593716)
Affinity DataIC50:  302nMAssay Description:Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair