BDBM50104344 1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4,5-dihydro-oxazol-4-ylmethyl]-4-phenyl-piperazine::CHEMBL315564

SMILES COc1ccc(Br)cc1C1=N[C@@H](CN2CCN(CC2)c2ccccc2)[C@@H](C)O1

InChI Key InChIKey=XHTCEJWQQIHAOR-UZLBHIALSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50104344   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  290nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  290nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D4 expressed in CHO cells; High binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  2.40E+3nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  2.40E+3nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  3.50E+3nMAssay Description:In vitro for its ability to displace [3H]- SCH 23390 from Dopamine receptor D1 in bovine striatal membrane expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  3.50E+3nMAssay Description:In vitro for its ability to displace [3H]- SCH 23390 from Dopamine receptor D1 in bovine striatal membrane expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  3.70E+3nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50104344(1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4...)
Affinity DataKi:  3.70E+3nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed