BDBM50104708 (S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-yl)-2-(phenylsulfonamido)propanamide::2-Benzenesulfonylamino-N-[5-(4-methoxy-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-propionamide::CHEMBL419750

SMILES COc1ccc(cc1)C1=NN=C(NC(=O)[C@H](C)NS(=O)(=O)c2ccccc2)SC1

InChI Key InChIKey=VTRJTXRAOIMSTL-ZDUSSCGKSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50104708   

TargetNeutrophil collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  320nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  339nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  340nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  520nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  580nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  590nMAssay Description:In vitro inhibitory activity against the catalytic domain of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104708((S)-N-(5-(4-methoxyphenyl)-6H-1,3,4-thiadiazin-2-y...)
Affinity DataKi:  1.33E+3nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed