BDBM50104713 (S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)-2-(phenylsulfonamido)propanamide::2-Benzenesulfonylamino-N-[5-(4-nitro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-propionamide::CHEMBL321213

SMILES CC(NS(=O)(=O)c1ccccc1)C(=O)NC1=N[N-][C+](CS1)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=UVGAWIJNBYCHSP-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50104713   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  130nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  260nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  260nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  280nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  282nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  290nMAssay Description:In vitro inhibitory activity against the catalytic domain of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104713((S)-N-(5-(4-nitrophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  300nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed